LEAP Magazine

Despite a very difficult year for all of us, remarkable things are being accomplished at Johns Hopkins Rheumatology, and I hope you will see that this issue of LEAP is […]

This is an unusual time, and this year’s LEAP reflects it well: we start with Covid-19’s very sickest patients, and a Hopkins-wide team’s groundbreaking efforts to illuminate an unusual response in their immune system.

We end with a remarkable patient with a rare autoimmune disease: the legendary musician, Peter Frampton, who is not only raising awareness and research funding, but changing medical advice about how to preserve muscle function.

Any builder will tell you that strength lies in the crosspieces, where framework or walls intersect.

This issue of LEAP celebrates intersections: between clinicians and biological scientists, between both of those groups and information scientists, between specialists of different disciplines.

Alice in Wonderland may come to mind as you read this issue of LEAP, because we are moving from the large to the small, and back again: A rheumatic disease is big, and its effect can be devastating. However, a disease such as rheumatoid arthritis, scleroderma, or Sjögren’s is, in fact, multiple diseases, each slightly different.

In this issue of LEAP you can read about our precision approach to an increasingly common illness, gout, to a rare illness linked to Sjögren’s, and to cancer patients who are developing some autoimmune-mediated complications. And we are especially excited to share with you a tremendous breakthrough in understanding how rheumatoid arthritis begins.