• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer

Johns Hopkins Rheumatology

Show Search
Hide Search
  • About Us
    • Our History
    • Our Faculty
    • Rheumatology Fellowship
    • Administrative Core
    • Contact Us
    • eNews Signup
  • Make an Appointment
    • Clinic Information
    • Specialty Clinics
  • Our Research
    • Current Research Studies
    • Andrade Lab
    • Antiochos Lab
    • Casciola-Rosen Lab
    • Darrah Lab
    • Konig Lab
    • RDRCC
    • Bayview Immunomics Core (BIC)
  • Charitable Giving
    • Dr. John Welton Fellowship in Rheumatology
    • Dr. Ira T. Fine Discovery Fund
    • Dr. Nadia D. Morgan Memorial Fund
  • News
    • LEAP Magazine
  • Education
    • Advances in the Diagnosis and Treatment of the Rheumatic Diseases Course
    • RheumTV – Patient Education Video Library
Home / Research Studies / Clinical Trial: An Open-Label Pilot Study of Pioglitazone in Sporadic Inclusion Body Myositis

Clinical Trial: An Open-Label Pilot Study of Pioglitazone in Sporadic Inclusion Body Myositis

May 4, 2018 By Johns Hopkins Rheumatology

Receive the Latest News from Johns Hopkins Rheumatology

Receive the Latest News from Johns Hopkins Rheumatology

Join our mailing list to receive the latest news and updates from Johns Hopkins Rheumatology.

Interested In

You have Successfully Subscribed!

IRB: IRB00130996

Purpose of Study: Recruitment is underway in Baltimore for a research study of pioglitazone (a.k.a. Actos) for inclusion body myositis (IBM). This research is being done to find out if the drug pioglitazone will affect mitochondria in the muscle of IBM patients. We will also determine if pioglitazone is safe in people who have IBM.

Eligibility Criteria:

Study volunteers must meet the following criteria:
  • Age ≥ 50
  • Have a diagnosis of sporadic inclusion body myositis
  • Able to walk at least 20 feet, with or without the use of an assistive device
  • Able to rise from a chair without support from another person or device
  • No history of diabetes mellitus or prior or concurrent treatment with any diabetes therapy
  • Willing to come in for 6 on-site visits over 12 months
  • Willing to undergo 3 needle muscle biopsies
  • Additional criteria apply and will be reviewed with the study team

Study Status:

Recruiting

Coordinator/Contact:

Myositis Center
(410) 550-1741

Principal Investigator:

Jemima Albayda, MD
Assistant Professor of Medicine

Dr. Albayda's research involves harnessing muscle ultrasound for the evaluation of inflammatory muscle disease. Together with collaborators from the Applied Physics Lab, she is pioneering work applying machine intelligence to ultrasound interpretation in order to decrease the subjectivity and allow for automated tools. She is also involved in multimodal collaborative studies with Radiology, and works with other investigators in the Division of Rheumatology to provide an imaging assessment for their studies. She is the principal investigator for an investigator-initiated trial for Pioglitazone in Inclusion Body Myositis.

Use of this Site

All information contained within the Johns Hopkins Division of Rheumatology website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website.

Primary Sidebar

RheumTV Logo

Rheum.TV is an educational platform created to help patients living with a rheumatic disease. With over 100 disease education videos produced by the team at Johns Hopkins Rheumatology.

Visit RheumTV

Footer

Rheumatology Specialty Care Centers

  • Johns Hopkins Arthritis Center
  • Johns Hopkins Lupus Center
  • Johns Hopkins Lyme Disease Research Center
  • Johns Hopkins Myositis Center
  • Johns Hopkins Scleroderma Center
  • Johns Hopkins Sjögren’s Syndrome Center
  • Johns Hopkins Vasculitis Center

Connect with Us

  • Facebook
  • Twitter
  • YouTube
U.S. News and World Report Rankings Badge

Johns Hopkins Medicine

© 2025 Johns Hopkins Rheumatology - Patient Privacy