Younger patients with a specific form of myositis associated with antibodies to a protein called HMGCR have a worse prognosis than older patients.
Medical record review of patients admitted to the Johns Hopkins Hospital over 20-years, revealed that pneumocystis jiroveci pneumonia infection is a rare but persistent risk for patients with rheumatic diseases.
The study provides new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory autoimmune response characteristic of chronic, joint-destroying rheumatoid arthritis (RA). The new findings have important implications for prevention and treatment of RA.
A new biomarker discovered using cutting-edge technologies is found in people who develop scleroderma and cancer within a short period of time.
On Saturday October 15, 2016, the Hopkins Rheumatology CARES (Centers Advancing RESearch) team was out in full force to support the “Myositis Run, Walk, n’ Roll 5k” event at Centennial Park in Columbia, MD.
This study explored the relationship between subtypes of demyelinating disorders and Sjogren’s syndrome. These findings help identify the spectrum of neurological disease directly attributable to SS.
Patients and physicians came together in this international project to agree on what is critical to be measured in psoriatic arthritis clinical trials. This project was critical in defining what outcomes are important for both patients and their doctors.
The authors found that just very few patients reach durable remission, regardless of defining remission on-treatment or off-treatment. The higher the patients’ disease activity and treatment was when they entered our analysis, the lower was their chance of achieving remission.
Our study was to evaluate changes in transaminase levels (AST/ALT) over one week after methotrexate was given to rheumatoid arthritis patients. We evaluated 13 patients with RA taking stable doses of methotrexate, and then sequential blood samples were obtained over the course of 7 days.